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Image Search Results
Journal: Nature
Article Title: Targeting G1–S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors
doi: 10.1038/s41586-025-09433-w
Figure Lengend Snippet: Live-cell imaging of NCI-H1048 cells treated with CIRc-004. Time-lapse fluorescence microscopy of NCI-H1048 cells expressing H2B–GFP treated with 20 nM cyclin A/B RxL inhibitor (CIRc-004) over 10 h. Magnification, ×20.
Article Snippet: Then 300 μl of lysate was immunoprecipitated by rotating overnight at 4 °C with rabbit anti-HA epitope (Cell Signaling, 3724, 1:100) for exogenous cyclin B, rabbit anti-CDK2 E8J9T (Cell Signaling, 18048, 1:100) or equivalent amount of rabbit (DA1E) monoclonal antibody IgG XP isotype control (Cell Signaling, 3900).
Techniques: